Thirty-eight people are feared dead after a fire tore through a psychiatric hospital on the outskirts of Moscow.
The blaze broke out in the hospital in the town of Ramenskoye, around 70 miles (120 km) east of Moscow, at around 2.20am local time.
When firefighters arrived at the scene, the entire one-storey building was engulfed in flames, reports said.
There were believed to have been 41 people in the building when the fire broke out - 36 patients, two doctors and three nurses. Only one nurse and two patients are thought to have escaped the building.
Only one nurse and two patients are thought to have survived the blazeIrina Gumennaya, a spokeswoman for the Russian Investigative Committee, said at least 29 people were burned alive.
Many of the patients were on sedatives and most of them did not wake up, Yuri Deshekvykh of the emergency situations ministry told RIA Novosti.
Some of the windows of the building were barred and people were unable to get to fire exits.
The blaze is thought to have been started by an electrical short-circuit.
Emergency services said the patients ranged in age from 20 to 76.
Health Ministry officials said it took firefighters an hour to get to the hospital because a local ferry across the river was closed and they were forced to make a detour.
Moscow region governor Andrei Vorobyev told state television the fire alarm appeared to have worked, but the fire spread too quickly after igniting in a wooden annex.
Dmitry Pestov, deputy head of the Moscow region, added: "Fire safety watchdogs constantly check all (public) institutions and issue recommendations.
"As far as I know, all the recommendations had been followed. There are different versions, including arson and a short circuit. They will be checked."
Fires at state institutions in Russia such as hospitals, drug treatment centres and homes for the elderly have caused numerous casualties in recent years and raised questions about safety measures and conditions.
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